Mon 16th March – “Antioxidants and vascular dysfunction in atherosclerosis”

Dr Richard Siow, King’s College London

Dr Siow’s research follows two linked strands. The first is the investigation of antioxidant genes in vascular protection and whether oxidized lipids, cytokines and growth factors modulate the expression of antioxidant genes thus contributing to vascular dysfunction in atherosclerosis, diabetes and pre-eclampsia. His second interest is the effect of dietary antioxidants and soy phytoestrogens on reversing the endothelial and smooth muscle cell dysfunction associated with diabetes, pre-eclampsia and atherosclerosis. He employs nutrigenomic approaches to identify whether dietary factors modulate vascular gene expression to provide mechanistic insights for dietary prevention of vascular diseases.

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